Get The Care You Deserve At A Cancer Research Center

If you or someone you know is diagnosed with cancer, you should look for a cancer research center to go to. Even though to many, this may seem like a death sentence, this disease is not as lethal as it used to be. Thanks to advancements in science and technology, it is now much easier to take on this horrible disease and win.

It is understandable that you may be feeling angry, scared, and alone, but try and remember there are places you can go to get support. With the help, devotion, and care from the staff at your healthcare facility, it is possible for you to live a happy and fulfilling life while you fight this disease.

Keep in mind that everyone that has is disease will not experience all of the discomforts associated with it. However, there are a large number of people who do experience pain in addition to the other effects this disease causes. While you are battling this disease, you need to be surrounded and supported by people who are genuinely concerned about your wellbeing. Even though you don’t have a choice in whether or not you have the disease, you do have a choice in where you go to receive the treatment and support you need.

By going to a cancer research center you can hopefully stop this disease in its tracks. You don’t want to procrastinate and put getting treatment off because this disease can continue to grow and affect other areas of your body. Even though it is known as a silent killer, it doesn’t have to be one for you. It is possible for you to overcome this situation, but you can’t do it alone. Get the help and support you need. Not just from your loved ones, but also from medical professionals that care. Even though you may not think that this will make any difference in your outcome, there are plenty of studies that show that medical treatment that is administered by compassionate and caring staff in a soothing and comfortable setting is much more successful than any other kind of treatment.

Take advantage of the opportunity that is being provided when you seek treatment at this facility. If you are going to fight this disease with everything possible, you should do it in a manner that is most comfortable, affordable, and convenient for you. It doesn’t matter what stage of the disease you are in. It is never too late to start looking for a cancer research center that can help you overcome it.

Receive the treatment you need at a cancer research center. West Jefferson Medical Center can help you overcome your disease. For more information, visit: http://www.wjmc.org.

Breast cancer

Breast cancer is a cancer, which develops in breast tissues. It affects ducts carrying milk and glands making milk. Gland making milk is known as lobules. It may occur in both men and women but it is more common in women and is rare in men. Breast cancer can affect different tissues of the breast. It can affect ducts or tube moving milk from the breast to the nipple or milk producing parts lobules. It may be invasive or spreading from the milk duct or lobule to other tissues in the breast. It may also be non-invasive or confined to a smaller part of breast or in situ. Breast cancer in situ may affect the lining of the milk ducts or lobules and not invade nearby tissues. It may progress to invasive cancer.

Many patients may suffer from estrogen sensitive breast cancer. These types of breast cancer have receptors for estrogen on the surface of their cells. They are also known as estrogen receptor-positive cancer or ER-positive cancer. Some breast cancers may HER2-positive. HER2 is a gene helping cells growth, division or repair. This type of breast cancer quickly spreads and is more likely to be recurring.

Types of Breast Cancer

Breast cancers are primarily of two types Invasive Breast Carcinoma (IBC) or non-invasive (Carcinoma In Situ).

Invasive Breast Carcinoma (IBC) is further classified as :-

Invasive Lobular Carcinoma (ILC) – Invasive lobular carcinoma affects the lobules, the gland, which produces milk. It could spread to other parts of body as well. It is capable of entering the bloodstream or the lymphatic system and could travel with it. It could lead to thickening of the breast. It is more common in women above 45 years of age. Invasive Ductal Carcinoma (IDC) – It is the most common invasive breast cancer. It develops in milk ducts and spread to nearby tissues. It may also affect other parts of the body like bone, brain, liver, and lungs through blood or lymphatic system. In this type of breast cancer, lump growth is hard and irregularly shaped. Women, who are more than 40 years of age, are more likely to develop this disease. Non-Invasive or Carcinoma In Situ is further classified into two types, which are discussed below.

Lobular Carcinoma In Situ (LCIS) – It affects only lobules or glands that produce milk. Tumors in this type of cancer consist of small uniform cells. These cells are similar to cells of breast lobules. It is more common in women nearing menopause or between 40 and 50 years of age. It may not show up in mammogram and may not form lump. These tumors are usually HER2 negative (-) and belong to estrogen receptor-positive cancer or ER-positive cancer. It is highly treatable and is treated with hormone therapy. Ductal Carcinoma In Situ (DCIS) – Ductal carcinoma in situ is confined to the milk ducts of the breast. Tumors are made of irregular cells. They are nearly similar to cells of breast ductal system. It can be detected through mammograms as they form lumps. Most cases of this type of cancer not spread to other parts of body but some may change to invasive breast cancer (IBC). It is treated with surgery with or without radiation. It may be recurring. Thus treatment plan is devised after considering nuclear grade, cell necrosis, and cell and tumor architecture. This type of breast cancer is ER positive.

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Symptoms Of Inflammatory Breast Cancer

Inflammatory breast cancer takes lives of most of the people who develop it. It is a very “hostile” type of cancer, which thankfully, is also rare. It gets its name from the inflammation the breasts of the victim develop. Contrary to other forms of cancer, inflammatory breast cancer can develop in relatively younger females, too. Rarely do men develop IBC.

In Inflammatory breast cancer, the cancer cells block lymph vessels of the breast. This gives rise to the apparent inflammation and redness of the breast of a person diagnosed with IBC. Other forms of cancer usually develop in women as they age, but that is not the case with IBC. It can occur in young women, too. It is also said that African American women are more prone to developing IBC, and at a younger age too, compared to White women.

Inflammatory breast cancer can start showing symptoms early on, and become very advanced within a matter or few days. This can be very sad, especially when women delay seeking medical advice regarding the symptoms, as the cancer can advance very rapidly, and it can be very late already, when they seek medical help. However, the symptoms for IBC are so alarming that women almost immediately seek advice, and this is one reason for relatively earlier diagnosis of Inflammatory breast cancer, in most cases.

The unique characteristic of Inflammatory breast cancer is that no lump formation is associated with it. This characteristic makes it all the more dangerous, because mammography and ultrasound can not detect it, and it often goes undiagnosed, or misdiagnosed. Biopsy is the best method for diagnosing IBC.

The typical attributes of Inflammatory breast cancer are extreme redness, purple-ish bruised appearance, and swelling of the breast, which makes it look inflamed, hence the cancer’s name. The blocking of the lymph vessels by the cancer cells is the reason for both redness and swelling. Continual itching, a fast and constant increase in size of the breast, inverted nipples, tenderness, aches, heavy and burning sensations are all associated with Inflammatory breast cancer. Sometimes, the skin of the breast may also appear pitted, medically called peau d’orange, and this is due to swelling and accumulation of fluids. Also, the areola or the skin around the nipple can change in color, the skin of the nipple can swell, and lymph nodes on either side of the collarbone and under the arm can swell.

IBC is often misdiagnosed as mastitis, a breast cancer infection accompanied with redness and swelling of the breast. The most important thing to remember here is that symptoms persist even after two weeks of treatment for IBC, which is not the case with mastitis. It is also good to know that previous chest operations may partially block your breast lymph vessels, and this is not a breast cancer condition.

The treatment for Inflammatory breast cancer has greatly improved over the last few years. When the mortality rate used to be 100% few years back, today, around 60% women diagnosed with IBC live through their natural life-span. For treating IBC, a combination of therapies is required. Doctors usually start with chemotherapy and hormonal treatment, and follow it up with neoadjuvant therapy and mastectomy, after which, radiation therapy is highly recommended to prevent a recurrence of cancer.

The high mortality rate, the extensive treatments, the fear because of uncertainty of results, and all the other woes Inflammatory breast cancer can bring you will naturally put you down and scare you. Your fear is justified, but you must remember that technology has advanced exponentially over the last few years. If you keep hope, all the technology will just go into curing you.

Exemestane Has Mild Side Effects Can Prevent Breast Cancer

Exemestane has a good tolerability, has mild side effects. The Common side-effects including hot flashes, nausea, insomnia, depression, headaches, dizziness, pain, rash, abdominal pain, anorexia, vomiting, depression, hair loss, body or lower extremity edema, constipation and indigestion. Exemestane is an effective steroidal aromatase inactivator with superior tolerability, safety and efficacy in the adjuvant, neo-adjuvant and metastatic therapy of breast cancer. Exemestane is used for adjuvant treatment after tamoxifen treatment. The post-menopausal women patients with advanced breast cancer can accept such treatment.

Clinical trials show that the standard dose of exemestane is 25mg daily, There are 7.4% of patients give up treatment because of side effects In an interview with tamoxifen and exemestane adjuvant treatment of early breast cancer patients. The most commonly reported adverse reactions were hot flashes (22%), arthralgia (18%) and fatigue (16%). There are 2.8% of the patients appear side effects In all patients with advanced breast cancer. The most commonly reported adverse reactions were hot flashes (14%) and nausea (12%). Most Exemestane side effects is a normal pharmacology response (hot flushes), Because estrogen is blocked. Exemestane treatment for advanced breast cancer patients Rare with thrombocytopenia or leukopenia report. There are 20% of patients with episodic lymphopenia, Particularly past history of lymphopenia, but these patients had no symptoms of viral infection. There is no Exemestane side effect report in the treatment of early breast cancer.

Overall, exemestane has a good tolerability, with mild to moderate side effects. In the IES study, The rate of patients discontinued treatment is 6.3% of exemestane, Tamoxifen group was 5.1%. Although women may get the health from two new drugs, 4% of women taking these two drugs. Exemestane has no side effects than either drug. Subjects were 4560 postmenopausal women from Canada, the United States, France and Spain. Half of them taking exemestane, After three years, researchers found that only 11 of these people who suffer from breast cancer, without taking the drug have 32 people suffering from breast cancer. Exemestane can prevent breast cancer, The drug has been in the domestic market. If the people without breast cancer take exemestane before can reduce 60% the risk of breast cancer. Exemestane is an effective steroidal aromatase inactivator with superior tolerability, safety and efficacy in the adjuvant, neo-adjuvant and metastatic therapy of breast cancer.

Esophageal Cancer Therapeutics – Pipeline Assessment And Market Forecast To 2017

Esophageal Cancer Therapeutics Market is forecast to Show High Growth Until 2017, The report identifies the key trends shaping and driving the global Esophageal Cancer Therapeutics market.

GlobalData estimates that the global esophageal cancer therapeutics market was valued at $243.8m in
2010, and is forecast to grow at a Compound Annual Growth Rate (CAGR) of 14% over the next seven
years, to reach $594.7m by 2017. This fast growth is primarily attributed to the strong pipeline and onset of four promising molecules from 2014 onwards. The HER-2 expressing patients have access to
Herceptin (transtuzumab) which is approved for HER2-overexpressing metastatic gastroesophageal (GE)
junction adenocarcinoma along with some widely used off-label drugs such as cisplatin and capecitabine
and ECF (epirubicin,cisplatin and 5-FU) which have gone off-patent.

GlobalData analysis shows that the esophageal cancer therapeutics pipeline is strong, with 35 molecules
in various phases of clinical development, including 31 first-in-class molecules. The four promising first-inclass products such as Avastin (bevacizumab), Erbitux (cetuximab), ramucirumab and Tykerb (lapitinib) in late stage pipeline are expected to hit the market around 2014. These products possess mechanisms of action different from currently used drugs. Thus the pipeline for the esophageal cancer therapeutics
market is strong.

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The esophageal cancer therapeutics market is represented by Herceptin and some off-label drugs.
Cisplatin, Xeloda (capecitabine) and ECF are mainly used drugs for treating esophageal cancer.
Paclitaxel and carboplatin, 5-FU and leucovorin are also used but they have low response rates.
Herceptin from Genetech/Roche is prescribed as the first line and second line form of drug therapy for the treatment of HER2-overexpressing metastatic gastroesophageal junction adenocarcinoma patients. There are no other drugs which have been approved for non HER-2 overexpressing patients of esophageal cancer. Any drug that could successfully cater to this untreated patient segment is expected to reap revenues from the esophageal cancer therapeutics market.

GlobalData, the industry analysis specialist, has released its new report, Esophageal Cancer Therapeutics – Pipeline Assessment and Market Forecasts to 2017. The report is an essential source
of information and analysis on the global Esophageal Cancer Therapeutics market. The report identifies
the key trends shaping and driving the global Esophageal Cancer Therapeutics market. The report also
provides insights on the prevalent competitive landscape and the emerging players expected to significantly alter the market positioning of the current market leaders. Most importantly, the report
provides valuable insights on the pipeline products within the global Esophageal Cancer Therapeutics
sector. This report is built using data and information sourced from proprietary databases, primary and
secondary research and in-house analysis by GlobalDatas team of industry experts.

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